Ferroptosis in cancer therapy: a novel approach to reversing drug resistance

Ferroptosis in cancer therapy: a novel approach to reversing drug resistance Ferroptosis is an intracellular iron-dependent form of cell death that is distinct from apoptosis, necrosis, and autophagy. Extensive studies suggest that ferroptosis plays a pivotal role in tumor suppression, thus providing new opportunities for cancer therapy. The development of resistance to cancer therapy remains a major challenge. A number of preclinical and clinical studies have focused on overcoming drug resista...